IsaBiome™ Daily Digestive Health System

A Breakthrough in Better Gut Health

Your gut health is a crucial part of your weight loss and wellness journey that’s neglected far too often. IsaBiome™ Daily Digestive Health System works as a complete system to improve gut health so you can feel better overall.*

Probiotics help restore friendly bacteria to support a balanced digestive system, a healthier gut microbiome, and immune health for better long-term wellbeing.*

A variety of digestive enzymes deliver immediate benefits to help ease occasional gas and bloating and help break down foods for better nutrient absorption, which helps support gut comfort.*

IsaBiome complements the Isagenix System and is designed to work with Shake Days and Cleanse Days.

Why You Need IsaBiome

The gut microbiome is the next frontier in health and nutrition. It affects everything: digestion, metabolism, weight management, immune support, and even your brain! You need a strategy to support and nurture your microbial diversity if you truly want to optimize your health. We’ve all heard “we are what we eat,” but even more important is how we utilize what we eat. Good nutrition and IsaBiome can help keep your gut on track so you can achieve what you want.

A Complete Solution

Many companies offer digestive enzymes and probiotics as separate products addressing separate needs. But Isagenix formulated these two unique products to complement one another for an immediate and long-term total digestive health solution. Each product delivers amazing digestive benefits on its own, but together, they deliver results unlike anything on the market.

Probiotics – Better Biodiversity and Potency

What you eat is the No. 1 influence on your microbiome, which is why IsaBiome Probiotics are designed with a diversity of scientifically supported strains. Our probiotics feature 25 billion colony-forming units (CFUs) per serving with 11 strains.

What does that mean? A more robust biodiversity of friendly bacteria to promote better gut health.*

Targeted Enzymes to Break Down Food

You’ll experience immediate results when you use IsaBiome Digestive Enzymes. The formula includes 15 different enzymes to help break down food, boost nutrient absorption, and help ease occasional gas and bloating.*

No Refrigeration Required!

We take extra care of our probiotic strains to guarantee the highest-quality product that’s fully functional for maximum potency. That’s why we have the IsaBiome 3-Stage Viability Guarantee so you’ll never have to refrigerate your product. With microencapsulation manufacturing, advanced moisture- and humidity-minimizing bottle technology, and stomach acid-resistant capsules for targeted delivery to your intestinal tract, every step of the IsaBiome system ensures peak viability and effectiveness.

Advanced Packaging

No expense was spared to ensure the IsaBiome bottle and capsule technology are the best in the market. The bottles use moisture-removing technology every time you open and close the cap to ensure the probiotics and enzymes don’t activate before they reach your gut. The enzyme capsule is fast-dissolving so it works quickly to digest food in your stomach, while the probiotic capsule is acid-resistant to help the probiotics survive the stomach acid to reach your gut, where they go to work.

  • What Is IsaBiome?
  • Why Do I Need IsaBiome?
  • How Does It Work?
  • System Support


4.9 Of 5 By 21 Users
July 07,2021
Nixie Greene

Great product!

June 04,2020
Dani Apgar

This is a great product. I've been using it for years.

May 20,2020
Cheryl Grenz

I never used a probiotic until I tried Isagenix. I bought one once but since it had to be refrigerated, rather than with my vitamins, I forgot to take it until I just threw it away. I don't forget Isabiome! Now I know why they are so important, I feel great.

February 04,2020
Mary Amato

I so appreciate this product. I feel more regular in my gut health. I started my daughter (19) on this product , she is a believer also.

January 11,2020
Joymarie DeFruscio

The digestive enzyme is particularly wonderful. Has helped quite noticeably!

December 21,2019
Linda Alexander

I have used Probiotics for years and believe they have had a positive impact on my overall intestinal health. What I love about the Isagenix Probiotics are their convenience of not needing to refrigerate which makes them easy to stock up on and for my extensive travel schedule I always have them available. I take one every morning with 8 ounces of water to start my day off healthy.

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

††† Transparency and accuracy are a top priority at Isagenix. We constantly strive to ensure that product information is complete, accurate, and current. However, at times, products may be unavailable or have different labels or attributes than those listed here.